Efficacy and safety of herbal spermicidal contraceptive, Consap
نویسندگان
چکیده
Consap is a locally acting, non-hormonal, herbal spermicidal contraceptive isolated from Sapindus mukorosii. It has been observed to be free from systemic side-effects such as nausea, vomiting and irregularities in the menstrual cycle. It is a woman-controlled reversible method which needs to be used before intercourse. It has additional antitrichomonas activity and is more vaginal-friendly. In the present study, 521 women volunteers in the reproductive age group have been screened at six centres. Of these, 470 were included in the trial covering 2076 months of Consap cream use with 2358 total cycles covered during the study. Out of a total, 324 cases who used this cream for at least 6 months and more were considered to have completed the trial. In this study only nine patient failures and four method failure pregnancies resulted with a Pearl index of 2.3, which is acceptable for the general population. This study thus shows that Consap cream when used as prescribed is an effective contraceptive. It is a good alternative for women who do not want to use oral contraceptive pills or intrauterine devices.
منابع مشابه
Evaluation of the Spermicidal and Contraceptive Activity of Platycodin D, a Saponin from Platycodon grandiflorum
BACKGROUND The extract of Platycodon grandiflorum has been reported to have effective spermicidal activity. This study was designed to evaluate the spermicidal and contraceptive activity, as well as the safety, of Platycodin D (PD), a major saponin in Platycodon grandiflorum. METHODS Using the computer-aided sperm analysis (CASA) test criteria, the sperm-immobilizing activity of PD was studie...
متن کاملThe spermicidal and antitrichomonas activities of SSRI antidepressants.
The study investigated spermicidal and antitrichomonas activities of selective serotonin reuptake inhibitor (SSRI) antidepressants with a view to generate new lead for development of dual-function spermicidal microbicides, which is an urgent global need. Fluoxetine, Sertraline, and Fluvoxamine exhibited both spermicidal and anti-STI (antitrichomonas) activities in vitro, whereas Paroxetine and ...
متن کاملبررسی آگاهی خانم های باردار شهر تهران از اثربخشی وایمنی درمانهای گیاهی و عملکرد آنان در طی دوران بارداری
Introduction: World wild use of complementary medicine especially herbal remedies and inadequacy of evidences for safety and efficacy of medicinal herbs during pregnancy is an important subject and needs especial attention. This study was performed to assess the knowledge of pregnant women in Tehran about the efficacy and safety of herbal medicine and their practice during pregnancy. Method...
متن کاملPlant immunomodulators for termination of unwanted pregnancy and for contraception and reproductive health.
Neem (Azadirachta indica) seed and leaf extracts have spermicidal, anti-microbial, anti-fungal and anti-viral properties. They are also immunomodulators that induce primarily a TH1 type response. These properties are being exploited to develop two different useful methods of fertility control. Neem extracts given orally at early post-implantation stage terminate pregnancy in rodents and primate...
متن کاملA Review on Spermicidal Activities of Azadirachta indica
In recent year, there were various types of contraceptives developed having different mode of action. These contraceptives are prepared from natural as well as synthetic sources. These contraceptives worked by prevent the fusion of sperm into ovum, change female hormonal levels and spermicidal activity. Many compounds with different pharmacological activity have been evaluated in vitro for thei...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2013